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Table 1 The characteristics of 173 patients with FIGO stages Ib-IIIb cervical squamous cell carcinoma before and after the radical hysterectomy and results of correlation analyses

From: Tumor invasion depth is a useful pathologic assessment for predicting outcomes in cervical squamous cell carcinoma after neoadjuvant radiotherapy

Characteristic   Number of patients, n (%) Median age, years (range) Distant metastasis, n (%) P Recurrence, n (%) P The death events within 5 years, n (%) P
Treatments CCRT 125(72.3 %) 45(25–65) 12(9.6 %) 0.579 4(3.2 %) 0.697 7(5.6 %) 0.512
  RT 48(27.7 %) 46(34–71) 6(12.5 %)   1(2.1 %)   4(8.3 %)  
FIGO stage Ib 5(2.9 %) 45(42–47) 0 0.003 0 0.319 0 <0.001
  IIa 3(1.7 %) 45(38–58) 0   0   0  
  IIb 150(86.7 %) 45(27–71) 13(8.7 %)   4(2.7 %)   5(3.3 %)  
  IIIb 15(8.7 %) 48(25–65) 5(33.3 %)   1(6.7 %)   6(40 %)  
yPathologic stage, * 84(48.6 %) 45(27–65) 3(3.6 %) 0.001 1(1.2 %) 0.150 1(1.2 %) 0.003
yI a1 24(13.9 %) 42(35–52) 2(8.3 %)   0   1(4.2 %)  
  yI a2 5(2.9 %) 43(32–57) 0   1(20 %)   1(20 %)  
  yI b2 61(35.2 %) 46(25–71) 13(21.3 %)   3(4.9 %)   8(13.1 %)  
WHO evaluation CR 83(48.0 %) 45(27–65) 3(3.6 %) 0.007 1(1.2 %) 0.206 1(1.2 %) 0.010
PR 88(50.9 %) 45(25–65) 15(17.0 %)   4(4.5 %)   10(11.4 %)  
  SD 2(1.2 %) 57(43–71) 0   0   0  
  PD 0 0 0   0   0  
RECIST1.1 CR 83(48.0 %) 45(27–65) 3(3.6 %) 0.005 1(1.2 %) 0.224 1(1.2 %) 0.007
  PR 90(52.0 %) 45(25–71) 15(16.7 %)   4(4.4 %)   10(11.1 %)  
  SD 0 0 0   0   0  
  PD 0 0 0   0   0  
TNR <90 % 102(59.0 %) 46(27–71) 11(10.8 %) 0.506 3(2.9 %) 0.789 8(7.8 %) 0.309
  >90 % 71(41.0 %) 45(25–65) 7(9.9 %)   2(2.8 %)   3(4.2 %)  
TRG TRG1 23(13.3 %) 46(36–58) 1(4.3 %) 0.176 0 0.925 0 0.119
  TRG2 70(40.5 %) 45(27–71) 7(10 %)   3(4.3 %)   5(7.1 %)  
  TRG3 44(25.4 %) 44(25–65) 4(9.1 %)   1(2.3 %)   1(2.3 %)  
  TRG4 33(19.1 %) 47(30–65) 5(15.2 %)   1(3.0 %)   4(12.1 %)  
  TRG5 3(1.7 %) 45(39–45) 1(33.3 %)   0   1(33.3 %)  
Lymph node metastasis yes 20(11.6 %) 46(37–65) 7(35.0 %) 0.000 3(15.0 %) 0.001 3(15.0 %) 0.093
no 153(88.4 %) 45(25–71) 11(7.2 %)   2(1.3 %)   8(5.2 %)  
  1. Note: Post-operative pathologic FIGO stage *: FIGO staging no longer includes Stage 0 (Tis)