Fig. 3
From: MDR-1 and MRP-1 activity in peripheral blood leukocytes of rheumatoid arthritis patients
Calculating the MAF-values. This figure shows the shifts in the Fl1-Calcein-signal with the different MDR-blockers. Part a shows the two parallel samples treated with the MDR1 and MRP1 blocker Verapamil (Fl1-Calcein mean 645.72 and 619.07). Part b shows the two parallel samples of the controls incubated in HBSS (Fl1 mean 406.42 and 428.39). Part c shows the two parallel samples treated with the MRP1 blocker MK-571 (Fl1-Calcein 436.39 and 389.89). With these Fl1-Calcein values the different MAFs of the CD3+ lymphocytes are as follows MAFTotal = 34, MAFMRP1 = 0, MAFMDR1 = 34