Table 1 The association between TRPV6 expression and clinicopathologic features in patients with ESCC
From: TRPV6 plays a new role in predicting survival of patients with esophageal squamous cell carcinoma
Characteristic | mRNA cohort | Protein cohort | ||||
|---|---|---|---|---|---|---|
Case | Downregulation (%) | P a | Case | Downregulation (%) | P a | |
Age | Ā | Ā | 0.827 | Ā | Ā | 0.407 |
āāā¤ā58 | 72 | 28(38.9) | Ā | 113 | 58(51.3) | Ā |
āā>ā58 | 102 | 38(37.3) | Ā | 105 | 48 (45.7) | Ā |
Gender | Ā | Ā | 0.298 | Ā | Ā | 0.093 |
āMale | 126 | 45(35.7) | Ā | 121 | 65(53.7) | Ā |
āFemale | 48 | 21(43.8) | Ā | 97 | 41(42.3) | Ā |
Location | Ā | Ā | 0.992 | Ā | Ā | 0.364 |
āUpper | 35 | 13(37.1) | Ā | 49 | 20(40.8) | Ā |
āMiddle | 94 | 36(38.3) | Ā | 152 | 76(50.0) | Ā |
āLower | 45 | 17(37.8) | Ā | 17 | 10(58.8) | Ā |
Differentiation | Ā | Ā | 0.133 | Ā | Ā | 0.398 |
āGrade 1 | 41 | 16(39.0) | Ā | 24 | 14(58.3) | Ā |
āGrade 2 | 91 | 29(31.9) | Ā | 147 | 67(45.6) | Ā |
āGrade 3 | 42 | 21(50.0) | Ā | 47 | 25(53.2) | Ā |
pT category | Ā | Ā | 0.089 | Ā | Ā | 0.073 |
āT1ā2 | 43 | 15(34.4) | Ā | 80 | 37(46.7) | Ā |
āT3ā4 | 131 | 64(48.8) | Ā | 138 | 82(59.3) | Ā |
pN category | Ā | Ā | 0.854 | Ā | Ā | 0.459 |
āN0 | 96 | 37(38.5) | Ā | 124 | 63(50.8) | Ā |
āN1ā3 | 78 | 29(37.2) | Ā | 94 | 43(45.7) | Ā |
Pathological staging | Ā | Ā | 0.827 | Ā | Ā | 0.365 |
āIāII | 101 | 39(38.6) | Ā | 137 | 67(48.8) | Ā |
āIII | 73 | 27(37.0) | Ā | 81 | 42(52.2) | Ā |