Table 2 Univariate analysis of TRPV6 expression and clinicopathological factors for disease specific survival in patients with ESCC

TRPV6 expression

0.531

0.244

 Downregulation

53.8

34.0

 Normal expression

59.6

42.9

Age

0.145

0.448

  ≤ 58

60.6

38.9

  > 58

55.3

38.1

Gender

0.653

0.880

 Male

58.1

40.2

 Female

55.9

37.2

Location

0.545

0.428

 Upper

64.4

30.6

 Middle

56.1

40.1

 Lower

55.2

47.1

Differentiation

0.330

0.010

 Grade 1

62.6

54.2

 Grade 2

60.7

40.8

 Grade 3

45.4

23.4

pT category

0.040

0.002

 T1–2

66.4

52.5

 T3–4

55.6

30.4

pN category

<0.001

<0.001

 N0

74.0

54.0

 N1–3

37.5

18.1

Pathological staging

<0.001

<0.001

 I–II

72.1

53.3

 III

37.5

13.6