Skip to main content
Fig. 2 | Diagnostic Pathology

Fig. 2

From: Abnormal villous morphology mimicking a hydatidiform mole associated with paternal trisomy of chromosomes 3,7,8 and unipaternal disomy of chromosome 11

Fig. 2

Partial genotypes of the patient, her partner and the villous tissue. a, b and c show genotypes in the parents and villous tissue following amplification of STR loci D3S1358, D7S820 and D8S1179 respectively. Trisomy of the villous tissue at these loci is demonstrated by the presence of two paternal alleles (c) or an increased dosage of a single paternal allele relative to the maternally derived allele (a, b). d shows an example of a disomic locus with one maternal and one paternal allele, found for loci on the majority of chromosomes. e and f represent loci on chromosome 11 for which the villous tissue has only paternally derived alleles

Back to article page