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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Increasing diagnostic accuracy to grade dysplasia in Barrett’s esophagus using an immunohistochemical panel for CDX2, p120ctn, c-Myc and Jagged1

Fig. 1

Hematoxylin & Eosin staining. a Non-dysplastic Barrett’s mucosa characterized by uniform, bland nuclei arranged in a surface monolayer. b Low-grade dysplasia exhibiting nuclear hyperchromasia, elongation and stratification extending up to the surface epithelium. c High-grade dysplasia depicting increased architectural and cytologic complexity including loss of nuclear polarity. d Intramucosal adenocarcinoma characterized by severe architectural distortion including angulated glands. (a-d, 100×)

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