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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Hepatocellular adenoma classification: a comparative evaluation of immunohistochemistry and targeted mutational analysis

Fig. 4

Patterns of glutamine synthetase staining in HCA. a, Diffuse GS staining in CTNNB1 wild-type tumor (case 4) (upper right, x 10). b, GS staining of bIHCA carrying both CTNNB1 and IL6ST alterations (case 7) shows perivascular and focal pseudomap-like pattern (lower aspect, x 10). As internal positive control, note the normal centrilobular pattern of GS staining of the adjacent non-neoplastic liver

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