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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Automated quantification of proliferation with automated hot-spot selection in phosphohistone H3/MART1 dual-stained stage I/II melanoma

Fig. 3

Comparison of the manual and automated index (a) and hot-spot selection (b). a Bland-Altman plot of manual and automated PHH3 counts in the global MART1-verified tumor area; three outliers with differences of -332, -125, and 259 cells/mm2 were excluded. b Bland-Altman plot of automated PHH3 counts in manually and automatically selected hot spots; two outliers with differences of -21 and 40 cells were excluded. In both plots, indices of manual procedures are subtracted from automated procedures. Mean difference between indices (\( \overline{d} \)), 95 % limits of agreement (LIM), and P-value of Wilcoxon signed rank tests are shown

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Diagnostic Pathology

ISSN: 1746-1596

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