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Fig 2 | Diagnostic Pathology

Fig 2

From: Diagnostic use of fluorescence in situ hybridization in expert review in a phase 2 study of trabectedin monotherapy in patients with advanced, translocation-related sarcoma

Fig 2

Representative images of sarcomatoid carcinoma after synovial sarcoma was excluded. a: The tumor had a pseudoglandular structure and a sheet-like proliferation of cuboidal tumor cells. b: Tumor cells were positive for cytokeratin AE1/AE3 on IHC. c: Tumor cells were negative for bcl-2 on IHC. Infiltrating lymphocytes alone were bcl-2 positive. d: FISH analysis revealed no SS18 split signals. Nuclei showed more than two pairs of orange and green signals with a polyploidy pattern (arrows)

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Diagnostic Pathology

ISSN: 1746-1596

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