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Fig 3 | Diagnostic Pathology

Fig 3

From: Diagnostic use of fluorescence in situ hybridization in expert review in a phase 2 study of trabectedin monotherapy in patients with advanced, translocation-related sarcoma

Fig 3

Representative images of poorly differentiated synovial sarcoma without cytokeratin expression. a: The tumor consisted of solid and fascicular proliferations of round to short-spindle tumor cells with round to oval nuclei. b: Tumor cells were negative for cytokeratin AE1/AE3 on IHC. c: Tumor cells were negative for EMA on IHC. d: FISH analysis revealed a pair of split and fused orange and green signals showing a SS18 split pattern (arrows)

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