Fig. 2

Triple-negative breast carcinoma showed diffusely strong positivity for EZH2. Typical histologic features such as high grade tumor cells arranged in cords and nest with prominent necrosis and pushing border were shown in HE stained section (a, Magnification × 100). The tumor cells were negative for HER2, ER, and PR (b, c, d, Magnification × 400), and showed high tumor proliferative index Ki67 (e, Magnification × 100). Strong overexpression of EZH2 was observed in high grade triple-negative breast carcinoma (f, Magnification × 400)