Table 3 Univariate analysis of associations between clinicopathological variables and patient outcome (N = 124^a)

Gender

0.03

0.9

 Female

 Male

2.7

(1.1–6.8)

1.1

(0.5–2.4)

Age

0.06

0.3

  > 65 years

  < 65 years

2.8

(0.9–8.6)

1.5

(0.7–3.3)

Histology

0.01

0.04

 Adenocarcinoma

 Squamous cell carcinoma

0.7

(0.3–1.8)

0.5

(0.2–1.2)

 Large cell carcinoma

9.6

(2.7–34.0)

4.7

(1.1–20.1)

pTNM

< 0.001

0.002

 I

 II

1.7

(0.6–4.5)

2.2

(0.8–5.7)

 III

8.8

(3.4–22.4)

7.1

(2.6–19.2)

pT

0.07

0.02

 pT1

1.7

(0.6–5.6)

 pT2

2.4

(0.8–7.2)

5.6

(1.7–18.2)

 pT3

4.8

(1.4–16.3)

 pT4

pN

0.001

0.005

 pN0

 pN1

3.6

(1.4–9.1)

3.5

(1.4–8.9)

 pN2

8.2

(2.9–23.0)

5.1

(1.7–15.8)

Tumor size

0.18

0.73

  ≤ 3.0 cm

  ≥ 3.1 cm

1.7

(0.8–3.9)

1.2

(0.5–2.6)

DTCs detected by IMS

0.18

0.77

 IMS negative

 IMS positive

1.7

(0.8–3.8)

1.1

(0.5–2.5)