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Table 1 Crosstabulation of p16-expression and other findings based on the HPV DNA status in 121 biopsy specimens evaluable for HPV DNA

From: Human papillomavirus infection and p16 expression in the immunocompetent patients with extragenital/extraungual Bowen’s disease

  DNA positive for HR α-HPV or β-HPV DNA negative for HR α-HPV and β-HPV p-value (Statistical test)
IHC p16    0.4247 (Fisher’s exact test)
   positive 34 68
   negative 8 10
   not evaluable 0 1
Sex    0.7039 (Fisher’s exact test)
   F 21 43
   M 21 36
Site    0.3560 (Fisher’s exact test)
   Sun-exposed 28 59
   Sun-protected 11 15
   Unknown 3 5
Solar elastosis    0.3349 (Fisher’s exact test)
   positive 21 48
   negative 21 31
Koilocyte-like changes    0.1781 (Fisher’s exact test)
   positive 21 29
   negative 21 50
Papillomatosis    0.3170 (Fisher’s exact test)
   Positive 17 25
   Negative 24 54
   Unknown 1 0