Table 4 Multivariate analysis for disease-free survival and overall survival
From: Expression of amphiregulin predicts poor outcome in patients with pancreatic ductal adenocarcinoma
Parameter | HR | 95 % CI | P |
|---|---|---|---|
Disease-free survival: Cox regression model | |||
TNM stage | 0.06 | ||
III-IV (vs. I-II) | 2.528 | 1.299–4.921 | |
Tumor differentiation | 0.021 | ||
Poor (vs. Well/moderate) | 1.785 | 1.089–2.925 | |
AREG expression | 0.168 | ||
Positive (vs. Negative) | 1.418 | 0.863–2.331 | |
AREG/EGFR coexpression | 0.587 | ||
Negative (vs. Positive) | 0.922 | 0.687–1.237 | |
Overall survival: Cox regression model | |||
Tumor size | 0.485 | ||
T3-4 (vs. T1-2) | 1.24 | 0.677–2.271 | |
TNM stage | 0.03 | ||
III-IV (vs. I-II) | 2.25 | 1.081–4.684 | |
Tumor differentiation | 0.004 | ||
Poor (vs. Well/moderate) | 2.125 | 1.277–3.537 | |
Resection margins | 0.045 | ||
Positive (vs. Negative) | 1.84 | 1.277–3.537 | |
Lymph node metastasis | 0.417 | ||
Yes (vs. No) | 1.233 | 0.743–2.048 | |
AREG expression | 0.03 | ||
Positive (vs. Negative) | 1.822 | 1.058–3.137 | |