Table 2 Clinical and treatment features of 26 PPMSSs
Case NO. | Age/Gender | Symptoms/preop course at initial Op | Smoking | Size (CM) | Location | Microscopically invasion | Microscopically margin | Lymph node metastasis | Treatment | Progression/interval | Outcome/Follow-up duration |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M/48 y | Cough, Dyspnea/24 m; Chest pain/1 m | NA | 15 | RLL | NA | NA | ND | Lobectomy | NA | NA |
2 | M/52 y | Cough, Expectoration, Blood in phlegm/4 d | NA | 3.5 | RLL | - | - | ND | Lobectomy | NA | NA |
3 | F/27 y | Cough, Expectoration/1 m | Never | 5 | RLL | pleura | - | - | Lobectomy, Lymph node dissection, Chemotherapy (EADM + IFO + DTIC) | NA | NA |
4 | F/42 y | Chest pain, Hemoptysis/6 m | Never | 13 | RMLL | pleura | - | - | Lobectomy, Lymph node dissection | NA | NA |
5 | M/30 y | Cough, Chest pain/15 d | 10 y | 24 | LP | ND | ND | ND | Chemotherapy (IFO + EADM + DDP) | NA | NA |
6 | M/27 y | Cough, Chest pain, Dyspnea/6 m; Blood in phlegm/1 w | Never | 15 | LLUL | ND | ND | ND | Biopsy only | Local lymph node metastasis/at presentation | DOD/11 m |
7 | F/53 y | Cough, Hemoptysis/6 m | Never | 6 | LUL | - | - | - | Lobectomy, Lymph node dissection, Chemotherapy (CTX + VCR + EADM) | Localized/45 m | DOD/51 m |
8 | M/20 y | Cough, Chest pain/NA | NA | 3 | RML | ND | ND | ND | Biopsy only | Intrapulmonary metastasis/at presentation | DOD/8 m |
9 | F/31 y | Cough, Dyspnea/2 m | NA | 15 | Anterior mediastinum | NA | NA | ND | Tumorectomy | Localized/6 m | DOD/12 m |
10 | F/72 y | Cough, Expectoration/3 d | NA | 5 | RLL | pleura | - | NA | Lobectomy, Lymph node dissection | Intrapulmonary metastasis/29 m | DOD/32 m |
11 | M/28 y | Cough/24 m; Hemoptysis/2 d | NA | 6 | LUL | - | - | NA | Lobectomy, Lymph node dissection | NA | NA |
12 | M/62 y | Cough, Blood in phlegm/3 m | 30 y | 11.6 | LL | ND | ND | ND | Bronchial artery infusion chemotherapy (FudR + DDP + NVB) | Intrapulmonary and thyriod metastasis/at presentation | DOD/15 m |
13 | F/34 y | Cough, Expectoration, Hemoptysis/1 m | Never | 3.5 | LLL | - | - | - | Lobectomy, Lymph node dissection, Chemotherapy (IFO + EADM) | Localized/26 m; Left chest wall/36 m;Left rib/39 m; Right lung and spine metastasis/51 m | AWD/52 m |
14 | M/26 y | Cough, Chest pain, Dyspnea/20 d | 7 y | 14 | LUL | pleura | + | ND | Lobectomy | Localized/8 m | DOD/11 m |
15 | F/38 y | Cough, Chest pain/NA | NA | 8 | LUL | NA | NA | ND | Lobectomy | NA | NA |
16 | F/46 y | Cough, Chest pain/24 m | Never | 2.3 | RUL | ND | ND | ND | Biopsy only | Brain metastasis/at presentation | DOD/10 m |
17 | F/39 y | Cough, Chest pain/1 m | Never | 10 | LUP | Lung; chest wall | - | - | Lobectomy, Lymph node dissection, Chemotherapy (DTIC + EADN) | Adrenal gland metastasis/2 m | DOD/15 m |
18 | M/46 y | Cough/NA | NA | 4.2 | LUL | - | - | ND | Lobectomy | Multiple organs metastasis/2 m | DOD/18 m |
19 | M/20 y | Asymptomatic | Never | 3.5 | RUP | - | - | ND | Tumorectomy, Chemotherapy (IFO + DDP + EADM), Radiotherapy | Left lung metastasis/24 m | AWD/24 m |
20 | M/36 y | Asymptomatic | Never | 4.5 | LLL | - | - | - | Lobectomy, Lymph node dissection | NO | NED/4 m |
21 | M/16 y | Cough, Hemoptysis/NA | Never | 6 | RL | pleura | + | ND | Partial tumorectomy | NO | DOD/18 m |
22 | M/22 y | Chest pain/2 w; Spontaneous hemopneumothorax/1+ w | 6 y | 5 | LP | lung | + | ND | Tumorectomy | NO | DOD/9 m |
23 | M/47 y | Chest pain, Dyspnea/5 m | 30 y | 18 | RL | ND | ND | ND | Chemotherapy (GT regimen) | NO | AWD/10 m |
24 | M/60 y | NA | 30 y | 7 | LUL | - | - | - | Lobectomy, Lymph node dissection, Postoperative | Localized/9 m | AWD/9 m |
25 | M/37 y | Cough, Expectoration,Chest pain, Dyspnea/1 m | 10 y | 4 | LUL | - | - | - | Lobectomy, Lymph node dissection | NO | NED/1 m |
26 | M/24 y | Dyspnea/3 m;Syncope/2 m | Never | 5.3 | Valvula bicuspidalis | myocardium | - | ND | Tumorectomy, Chemotherapy | Localized/2 m | DOD/26 m |