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Table 4 Multivariate analyses showing HRs for patient OS and DFS conferred FIGO stage, DEF6 and p16 expression (N = 180)

From: DEF6 expression in ovarian carcinoma correlates with poor patient survival

Variable

Overall survival (OS)

Disease-free survival (DFS)

HR

95 % CI

P -value

HR

95 % CI

P -value

FIGO stage

      

 I

 

1.00a

  

1.00a

  

 II

 

0.624

0.235–1.658

0.344

0.591

0.222–1.575

0.293

 III

 

1.480

0.563–3.890

0.426

1.373

0.522–3.609

0.520

 IV

 

3.845

0.734–20.133

0.111

3.496

0.671–18.206

0.137

DEF6

  

0.025*

  

0.016*

 Score 0 and 1

 

1.00a

  

1.00a

  

 Score 2 and 3

 

2.115

1.097–4.079

 

2.248

1.161–4.352

 

p16

  

0.611

  

0.611

 Score 0, 1 and 2

 

1.00a

  

1.00a

  

 Score 3

 

1.250

0.530–2.945

 

1.250

0.529–2.953

 
  1. aReference category for HR (Hazard Ratio) calculation with variable
  2. CI: Confidence Interval. (*Significant difference)