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Table 1 Clinical features, treatments and prognosis in four cases of MEITL

From: Multiple lesions of gastrointestinal tract invasion by monomorphic epitheliotropic intestinal T-cell lymphoma, accompanied by duodenal and intestinal enteropathy-like lesions and microscopic lymphocytic proctocolitis: a case series

 

Case 1

Case 2

Case 3

Case 4

Age (years)

60

40

50

70

Sex

M

F

F

M

Chief complaints

Diarrhea

Diarrhea

Abdominal distention

Nausea

Duration of chief complains (mons)

17

3

1

2

Total protein (g/dl)

4

4.4

6.6

6.4

Albumin (g/dl)

2.1

2.9

3.8

3

LDH (IU/l)

165

156

187

150

sIL2R (U/ml)

963

1419

4150

587

Anti-gliadin/-transglutaminase tests

−/−

ne

ne

ne

Helicobacter pylori IgG antibody

−

ne

−

+

Gastrointestinal perforation

−

+ (after treatment)

−

−

Bone marrow tumour invasion

+ (30 %)

−

+ (30 %)

+ (20 %)

Clinical stage

IV

I

IV

IV

Treatment (regimen)

CHASE, SCT

THP-COP, surgery

CHOP, SCT

SMILE

Response

Partial response

No response

Partial response

Partial response

Survival times (months)

36, dead

12, dead

9, dead

9, dead

  1. CHASE Cyclophosphamide, cytarabine, etoposide, dexametahsone, SCT Stem cell transplantation, THP-COP Pirarubicin, cyclophosphamide, vincristine, prednisolone, CHOP Cyclophosphamide, doxorubicin, vincristine, prednisolone, SMILE Dexamethasone, methotrexate, ifosfamide, L-asparaginase, etoposide; ne not examined