Table 2 Endoscopic and histological findings in the GI tract and cell-surface markers in four patients with MEITL
| Â | Case 1 | Case 2 | Case 3 | Case 4 |
|---|---|---|---|---|
Duodenal tumour lesions | Edematous mucosa | Edematous mucosa | Reddish granular mucosa | Submucosal tumors, pinhole-like stenosis |
Intestinal tumour lesions | Diffuse thickening, circumferential ulcers | Diffuse thickening, ulcerative tumours | Diffuse thickening | Diffuse thickening |
Colonic tumor lesions | Edematous mucosa | Edematous mucosa | Edematous mucosa with erosions and ulcers | Edematous mucosa |
Duodenal nonneoplastic lesion | Edematous mucosa, villous atrophy | Edematous mucosa, villous atrophy | Edematous mucosa, villous atrophy | Edematous mucosa, villous atrophy |
Intestinal nonneoplastic lesion | Diffuse edematous mucosa, villous atrophy | Diffuse granular mucosa, villous atrophy | Diffuse granular mucosa, villous atrophy | Diffuse granular mucosa, villous atrophy |
Colorectal nonneoplastic lesion | Edematous mucosa | Edematous mucosa | Edematous mucosa | Edematous mucosa |
Tumour invasion (S/D/I/C/R) | +/+/+/+ (cecum)/− | −/+/+/+ (cecum) /− | ne/+/+/+/+ | ne/+/+/+/+ |
Duodenal and intestinal enteropathy | + | + | + | + |
Lymphocytic proctocolitis | + | + | + | + |
Increase of reactive T-IELs (D/I/C/R) | +/+/+/+ | +/+/+/− | +/+/+/+ | +/+/+/+ |
CD103 | + | + | + | + |
TCR βF1 | + | − | + | − |
TCR CγM1 | − | + | − | + |
CD3 | + | + | + | + |
CD4 | − | − | − | − |
CD7 | + | + | + | + |
CD8 | + | + | + | + |
CD56 | + | + | + | + |
TIA1 | + | + | + | + |
CD5 | − | − | − | − |
CD30 | − | − | − | − |