Fig. 3

Histological features of angiomatous pleomorphic xanthoastrocytoma. a Spindle-shaped cells, arranged in fascicular and fibrillary patterns, are observed in focal areas. b, c Calcification and microcystic formation are present among the tumor cells. d In some areas, the small vessels and neoplastic astrocytes are in close proximity to each other, with capillaries adjacent to or extending between the tumor cells. e–g The cells include mono- or multinucleated giant astrocytes with a foamy or vacuolated cytoplasm. h Focal clusters of small lymphocytes and intranuclear inclusions are also evident. i–k EGB (intensely eosinophilic or pale) and eosinophilic hyaline droplets between tumor cells. l Less than one mitosis per high-power field. In each figure part, the corresponding histological features are indicated by arrows