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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Angiomatous pleomorphic xanthoastrocytoma: a case report and literature review

Fig. 4

Immunohistochemical and specific staining, and BRAFV600E mutation analysis. a Silver staining shows reticulin fibers encircling the blood vessels, but they are hardly present among tumor cells. b The EGBs stain red with PAS (Fig. 4b). cf The tumor cells are diffusely positive for GFAP, S100, and olig2, but negative for EMA. g, h The tumor cells are negative but the capillaries within the tumor are positive for CD34. i The tumor cells are negative for IDH1. j Approximately 50 % of the tumor cell nuclei stain positively for p53. k The Ki-67 labeling index is approximately 2 %. l The tumor was negative for a BRAFV600E mutation. In each figure part, the corresponding histological features are indicated by arrows

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