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Table 3 Results of Fisher’s exact test and Chi-squared test in comparison between REG-I positive and negative groups

From: Prognostic role of regenerating gene-I in patients with stage-IV head and neck squamous cell carcinoma

REG-I staining

Variables

REG-I positive

(N = 36)

REG-I negative

(N = 24)

P value

Age

  ≤ 65

  > 65

21

15

15

9

0.793

Sex

 Male

 Female

30

6

20

4

1.000

Lymphatic permeation

 Yes

 No

14

22

18

6

0.008

Vascular invasion

 Yes

 No

9

27

13

11

0.030

T-classification

 T1/T2

 T3/T4

15

21

7

17

0.416

N-classification (pretreatment)

 Yes

 No

35

1

22

2

0.558

Pathological lymph nodes

 Yes

 No

10

26

15

9

0.015

Grade

 Grade I

 Grade П

 Grade Ш

12

11

13

7

11

6

0.459a

Site of primary tumor

 Oropharynx

 Hypopharynx

 Tongue

 Larynx

8

5

0.944a

  1. aChi-squared test