Fig. 1
From: CDC73 gene mutations in sporadic ossifying fibroma of the jaws
Two novel somatic mutations of CDC73 identified in sporadic ossifying fibromas. Sequences of both peripheral blood (upper) showing the wild-type sequence and tumor (medium: directly sequencing. Lower: clone sequencing) are shown. a In case 1, c.13_16delCTTA (highlighted in small box), which leads to a frame shifting change with the fifth amino acid residue leucine as the first affected amino acid, changing into a alanine. b The other novel mutation, c.8_10delACGinsCT (highlighted in small box), was found in case 2. The frame shifted from the third amino acid residue aspartic acid that is changed into alanine