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Fig. 1 | Diagnostic Pathology

Fig. 1

From: MiR-424-5p participates in esophageal squamous cell carcinoma invasion and metastasis via SMAD7 pathway mediated EMT

Fig. 1

Downregulation of miR-424-5p in ESCC tissues and cell lines. a The expression levels of miR-424-5p were analyzed in ESCC tissues (T) and adjacent normal mucosa tissues (N) by real-time PCR method, RNU6B levels were used as an internal control. And the results of real-time PCR assay revealed down-regulation of miR-424-5p in ESCC tissue compare with adjacent normal mucosa tissues. **p < 0.01. b The expression levels of miR-424-5p were analyzed in ESCC cell lines (EC9706, Eca109 and EC-1) and immortal embryonic esophageal epithelium cell line (SHEE) by real-time PCR method, RNU6B levels were used as an internal control. Expression of miR-424-5p was down-regulated in EC9706, Eca109 and EC-1 compared with SHEE. **p < 0.01. The expression of miR-424-5p in EC-1 was the lowest in three kinds of ESCC cell lines although there had no statistical difference among them

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