Table 1 Summary of clinical and molecular-pathological characteristics^a

324 (100)

Age (range, median)

35-88, 63

 Male

194 (59.9)

183 (94.3)

11 (5.7)

97 (53.6)

84 (46.4)

80 (97.6)

2 (2.4)

 Female

130 (40.1)

90 (69.2)

40 (30.8)

61 (67.8)

29 (32.2)

40 (80.0)

10 (20.0)

 Smokers

147 (45.4)

139 (94.6)

8 (5.44)

75 (54.3)

63 (45.7)

65 (95.6)

3 (4.4)

 Former smokers

103 (31.8)

92 (89.3)

11 (10.7)

49 (53.8)

42 (46.2)

37 (97.4)

1 (2.6)

 Never-smokers

74 (22.8)

42 (56.8)

32 (43.2)

34 (81)

8 (19)

18 (69.2)

8 (30.8)

 I

26 (8.0)

22 (8.1)

4 (7.8)

8 (5.1)

11 (9.2)

7 (5.8)

0 (0)

 II-IIIA

63 (19.5)

51 (18.7)

12 (23.5)

31 (19.6)

20 (16.8)

28 (23.3)

1 (8.3)

 IIIB-IV

222 (68.5)

190 (69.6)

32 (62.7)

112 (70.9)

76 (63.9)

79 (65.8)

10 (83.3)