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Legend for normal values:
- s-creatinine 44 – 97 mcmol/L; s-albumin 32 – 55 g/L; u-24 h-protein <0,25 g/day; CH50 – total hemolytic classical complement pathway 72 – 128 %; AP50 – total hemolytic alternative complement pathway 80 – 120 E; C3 – C3 complement factor 920 – 1576 mg/L; C4 – C4 complement factor 162 – 445 mg/L; uMAC – complement lytic complex in urine <30 mcg/L; sMAC – complement lytic complex in serum 300 – 350 mcg/L
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Legend to the treatment:
- Methylprednisolone 3x pulse 10 mg/kg/day i.v. (Aug 12, 13, 14, 2011)
- Methylprednisolone 1 mg/kg/day p.o. (Aug 15 – Sep 22, 2011), thereafter slowly tapering dose
- Mofetil mycophenolate 2 x 1000 mg/day p.o. (Sep 10 – Dec 22, 2011)
- Resochine 1 tbl/day p.o. (Sep 20, 2011 – Sep 6, 2012)
- Tacrolimus kept at a desired level 5 – 7 mcg/L p.o. (Nov 22, 2011 – Jan 5, 2012)
- Rituximab 2 x 875 mg i.v. (Feb 3, 2012 and Feb 17, 2012)
- Cyclophosphamide 1000 mg i.v. (Apr 2, 2012) + 750 mg i.v. (Apr 30, 2012)
- Methylprednosolone 6x pulse 1 g i.v. (Apr 4, 5, 6, 7, 8, 9, 2012)
- Methylprednisolone 0,5 mg/kg/day p.o. (Apr 10 – May 15, 2012), thereafter slowly tapering dose)
- Plasmapheresis with fresh frozen plasma 32 sessions (May 3 – Aug 9, 2012)
- Eculizumab 900 mg/week 3-times, thereafter 1200 mg/2 weeks; ongoing (Aug 16, 2012)
- Methylprednosolone 3x pulse (Feb 24, 25, 26, 2014)
- Methylprednisolone 1 mg/kg/day p.o. (Feb 27 – Apr 3, 2014), thereafter slowly tapering dose, kept at 8 mg/2nd day
- Mofetil mycophenolate 2 x 1000 mg/day p.o. (Apr 3, 2014 - ongoing)
