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Table 1 Literature review of reported cases of mitotically active cellular fibroma

From: Rapid growth of mitotically active cellular fibroma of the ovary: a case report and review of the literature

         Immunohistochemistry  
Author(s) Age (y) Size (cm) PD Rupture Adhesion Surgery Mitoses (MF/10 HRP) Ki-67 PI Vimentin SMA α-inhibin Calretinin EMA Prognosis
Kaku et al. [11] 32 6.6 × 6.0 × 4.4 OT LSO 17 50 + + ND ND ND 12 month NED
Bucella et al. [12] 65 10.0 (First) OT TAH, BSO 4 9 + ND Focal+ ND ND Recurrence twice NED
12.0 (Second)
8.0 (Third)
Monteiro et al. [13] 13 19.0 × 15.0 × 12.0 OT Omentum RSO, OMT 5–7 ND ND ND ND ND ND 36 month NED
Wu et al. [14] 76 9.0 × 6.0 × 5.0 PM TAH, BSO 5–9 >10 + ND + ND
Zong et al. [15] 39 10.0 × 7.0 × 4.0 OT + Left latum & uterus TAH, LSO, OMT, AD, LD 3–5 10 + + ND ND 66 month NED
Yamada et al. [16] 36 6.0 OT ND LS (RSO) 10 8.7 + ND Focal+ 6 month NED
Present case 44 5.9 (First) Myoma LS (First), TAH, LSO, OMT (Second) 6.7 9.5 + + Focal+ 26 month NED
11.0 (Second)
  1. Abbreviations: α alpha, AD appendectomy, BSO bilateral salpingo-oophorectomy, EMA epithelial membrane antigen, HRP high power field, LD lymph node dissection, LS laparoscopic surgery, LSO left salpingo-oophorectomy, MF mitotic figure, ND not described, NED no evidence of disease, OMT omentectomy, OT ovarian tumor, PD preoperative diagnosis, PI proliferative index, PM pelvic mass, RSO right salpingo-oophorectomy, SMA smooth muscle actin, TAH total abdominal hysterectomy, y year, + positive, negative