Table 1 The significantly enriched GO_BP terms (top 1) and KEGG pathways of up-regulated DEGs
From: Potential molecular characteristics in situ in response to repetitive UVB irradiation
Term | Count | Gene lists | P-Value | Adjusted P-value |
|---|---|---|---|---|
GO_BP: enrichment Score: 3.4367879252049858 | ||||
 GO_BP: 0048066 pigmentation during development | 7 | DCT, SOX10, TYRP1, TYR, MLPH, KIT, GPR143 | 3.63E-08 | 5.65E-05 |
 GO_BP: 0043473 pigmentation | 7 | DCT, SOX10, TYRP1, TYR, MLPH, KIT, GPR143 | 5.78E-06 | 0.009009 |
 GO_BP: 0042438 melanin biosynthetic process | 3 | DCT, TYRP1, TYR | 1.59E-03 | 2.449285 |
 GO_BP: 0006582 melanin metabolic process | 3 | DCT, TYRP1, TYR | 2.03E-03 | 3.123208 |
 GO_BP: 0046148 pigment biosynthetic process | 4 | DCT, TYRP1, TYR, GPR143 | 3.30E-03 | 5.019067 |
 GO_BP: 0042440 pigment metabolic process | 4 | DCT, TYRP1, TYR, GPR143 | 4.96E-03 | 7.448208 |
 GO_BP: 0030318 melanocyte differentiation | 3 | SOX10, TYRP1, MLPH | 5.02E-03 | 7.534839 |
 GO_BP: 0050931 pigment cell differentiation | 3 | SOX10, TYRP1, MLPH | 5.76E-03 | 8.604376 |
KEGG | ||||
 hsa04080: Neuroactive ligand-receptor interaction | 6 | SSTR4, GPR156, KISS1R, OPRL1, NPBWR1, GRIN1 | 1.58E-02 | 13.80265 |
 hsa04916: Melanogenesis | 4 | DCT, TYRP1, TYR, KIT | 1.99E-02 | 17.11413 |
 hsa00350: Tyrosine metabolism | 3 | DCT, TYRP1, TYR | 2.73E-02 | 22.81886 |