Table 2 The significantly enriched GO_BP terms (top 1) and KEGG pathways of down-regulated DEGs
From: Potential molecular characteristics in situ in response to repetitive UVB irradiation
Term | Count | Gene lists | P-Value | Adjusted P-value |
|---|---|---|---|---|
GO_BP: enrichment Score: 2.505066250961214 | ||||
 GO_BP: 0030097 hemopoiesis | 7 | GPR183, INHBA, PTPRC, PLEK, CD8A, IKZF1, FLT3 | 1.38E-04 | 0.218579 |
 GO_BP: 0048534 hemopoietic or lymphoid organ development | 7 | GPR183, INHBA, PTPRC, PLEK, CD8A, IKZF1, FLT3 | 2.34E-04 | 0.369612 |
 GO_BP: 0050865 regulation of cell activation | 6 | INHBA, PTPRC, PLEK, IKZF1, FLT3, IL1B | 3.05E-04 | 0.482267 |
 GO_BP: 0002520 immune system development | 7 | GPR183, INHBA, PTPRC, PLEK, CD8A, IKZF1, FLT3 | 3.22E-04 | 0.509185 |
 GO_BP: 0030098 lymphocyte differentiation | 5 | GPR183, PTPRC, CD8A, IKZF1, FLT3 | 4.05E-04 | 0.638643 |
 GO_BP: 0002521 leukocyte differentiation | 5 | GPR183, PTPRC, CD8A, IKZF1, FLT3 | 1.00E-03 | 1.572197 |
 GO_BP: 0045619 regulation of lymphocyte differentiation | 4 | INHBA, PTPRC, IKZF1, FLT3 | 1.27E-03 | 1.98708 |
 GO_BP: 0045577 regulation of B cell differentiation | 3 | INHBA, PTPRC, FLT3 | 1.32E-03 | 2.064808 |
 GO_BP: 0030217 T cell differentiation | 4 | PTPRC, CD8A, IKZF1, FLT3 | 1.39E-03 | 2.173407 |
 GO_BP: 0051249 regulation of lymphocyte activation | 5 | INHBA, PTPRC, IKZF1, FLT3, IL1B | 1.57E-03 | 2.458734 |
KEGG pathways | ||||
 hsa04640: Hematopoietic cell lineage | 7 | CD8A, FLT3, CD1C, IL1B, CSF2RA, CD1E, IL1A | 1.18E-06 | 0.001103 |
 hsa04060: Cytokine-cytokine receptor interaction | 8 | INHBA, CCL22, FLT1, IL18RAP, FLT3, IL1B, CSF2RA, IL1A | 7.78E-05 | 0.072785 |