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Table 2 The significantly enriched GO_BP terms (top 1) and KEGG pathways of down-regulated DEGs

From: Potential molecular characteristics in situ in response to repetitive UVB irradiation

Term Count Gene lists P-Value Adjusted P-value
GO_BP: enrichment Score: 2.505066250961214
 GO_BP: 0030097 hemopoiesis 7 GPR183, INHBA, PTPRC, PLEK, CD8A, IKZF1, FLT3 1.38E-04 0.218579
 GO_BP: 0048534 hemopoietic or lymphoid organ development 7 GPR183, INHBA, PTPRC, PLEK, CD8A, IKZF1, FLT3 2.34E-04 0.369612
 GO_BP: 0050865 regulation of cell activation 6 INHBA, PTPRC, PLEK, IKZF1, FLT3, IL1B 3.05E-04 0.482267
 GO_BP: 0002520 immune system development 7 GPR183, INHBA, PTPRC, PLEK, CD8A, IKZF1, FLT3 3.22E-04 0.509185
 GO_BP: 0030098 lymphocyte differentiation 5 GPR183, PTPRC, CD8A, IKZF1, FLT3 4.05E-04 0.638643
 GO_BP: 0002521 leukocyte differentiation 5 GPR183, PTPRC, CD8A, IKZF1, FLT3 1.00E-03 1.572197
 GO_BP: 0045619 regulation of lymphocyte differentiation 4 INHBA, PTPRC, IKZF1, FLT3 1.27E-03 1.98708
 GO_BP: 0045577 regulation of B cell differentiation 3 INHBA, PTPRC, FLT3 1.32E-03 2.064808
 GO_BP: 0030217 T cell differentiation 4 PTPRC, CD8A, IKZF1, FLT3 1.39E-03 2.173407
 GO_BP: 0051249 regulation of lymphocyte activation 5 INHBA, PTPRC, IKZF1, FLT3, IL1B 1.57E-03 2.458734
KEGG pathways
 hsa04640: Hematopoietic cell lineage 7 CD8A, FLT3, CD1C, IL1B, CSF2RA, CD1E, IL1A 1.18E-06 0.001103
 hsa04060: Cytokine-cytokine receptor interaction 8 INHBA, CCL22, FLT1, IL18RAP, FLT3, IL1B, CSF2RA, IL1A 7.78E-05 0.072785
  1. Note: GO gene ontology, BP biological process, KEGG Kyoto encyclopedia of genes and genomes, DEGs differentially expressed genes. Count, the number of DEGs enriched in the corresponding term. The gene symbols were listed in accordance with the Gene database at NCBI (National Center for Biotechnology Information, http://www.ncbi.nlm.nih.gov/gene/?term)