Fig. 1From: Prognostic significance of mucin expression profiles in breast carcinoma with signet ring cells: a clinicopathological studySignet ring cells (SRCs) in invasive ductal carcinoma of no special type (a and b), invasive lobular carcinoma (c), and mucinous carcinoma (d). The intracytoplasmic lumen (ICL) type of SRCs is represented by discrete vacuoles with targetoid appearance (a and c), whereas the non-ICL type has abundant intracytoplasmic mucin dislodging the nucleus to one end of the cells, as seen in gastric carcinoma (b and d). Hematoxylin and eosin staining (a–d). Original magnification × 600 (a–d)Back to article page