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Table 3 Association of SRC population and types with clinicopathological profile

From: Prognostic significance of mucin expression profiles in breast carcinoma with signet ring cells: a clinicopathological study

 

SRC population

SRC type

 

<30 % (n = 10)

>31 % (n = 12)

 

ICL (n = 8)

Non-ICL (n = 14)

 

Age (years)

  > 65

4

7

0.39

5

6

0.37

  < 64

6

5

 

3

8

 

Histological type

 IDC

4

5

0.59

2

7

0.035

 ILC

5

4

 

6

3

 

 MC

1

3

 

0

4

 

Tumor size (cm)

  > 2.1

5

7

0.69

4

8

0.75

  < 2.0

5

5

 

4

6

 

Nuclear grade

 1

6

8

0.94

6

8

0.7

 2

2

2

 

1

3

 

 3

2

2

 

1

3

 

LN status

 Positive

5

3

0.22

2

6

0.4

 Negative

5

9

 

6

8

 

LVI

 Positive

5

2

0.09

2

5

0.6

 Negative

5

10

 

6

9

 

ER

 Positive

7

8

0.87

6

9

0.6

 Negative

3

4

 

2

5

 

TN vs other types

 TN

2

4

0.48

2

4

0.86

 Other types

8

8

 

6

10

 

Ki67 (%)

  > 20

4

2

0.22

2

4

0.86

  < 19

6

10

 

6

10

 

Recurrence

 Positive

1

1

0.89

1

1

0.67

 Negative

9

11

 

7

13

 
  1. Abbreviations: SRC signet ring cell, ICL intracytoplasmic lumen, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, MC mucinous carcinoma, LN lymph node, LVI lymphovascular invasion, TN triple negative