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Table 2 Survival analysis by univariate and multivariate methods to identify prognostic factors in HCC

From: SESN2 correlates with advantageous prognosis in hepatocellular carcinoma

 

Univariate analysis

Multivariate analysis

HR

p value

95% CI

HR

p value

95% CI

SESN2 expression

 High versus Low

0.271

0.001*

0.136–0.542

0.308

0.003*

0.140–0.678

Gender

 Male versus Female

1.140

0.732

0.539–2.414

   

Age (years)

  < 60 versus ≥60

1.630

0.084

0.937–2.838

   

Hepatitis B virus infection

 Positive versus Negative

1.111

0.900

0.526–1.539

   

Hepatitis C virus infection

 Positive versus Negative

1.799

0.036*

1.039–3.114

0.940

0.851

0.493–1.793

Liver cirrhosis

 Positive versus Negative

1.137

0.644

0.660–1.959

   

Tumour size (cm)

  > 5 versus ≤5

1.412

0.219

0.814–2.449

   

Lymph node metastasis

 Positive versus Negative

2.795

0.001*

1.621–4.821

1.839

0.063

0.968–3.495

Distant metastasis

 Positive versus Negative

2.709

0.003*

1.417–5.179

0.925

0.846

0.421–2.033

TNM stage

 Stage I-II versus Stage III-IV

0.276

0.001*

0.144–0.527

0.352

0.003*

0.178–0.696

  1. *p < 0.05