Fig. 3

Islet morphology is preserved with appropriate distribution of insulin- and glucagon-positive cells despite severe pancreas hypoplasia. Pancreas sections from individual II-B in Fig. 1 were stained using haematoxylin, phloxine and saffron staining (a), and immunohistochemistry for insulin, glucagon and somatostatin (b to d). Islets were identified (a) demonstrating normal morphology with central insulin (b), peripheral glucagon (c) and somatostatin staining (d). All images were photographed at 200× magnification