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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Double-hit lymphomas: clinical, morphological, immunohistochemical and cytogenetic study in a series of Brazilian patients with high-grade non-Hodgkin lymphoma

Fig. 1

Morphological, cytogenetic and immunohistochemical aspects of patient 1. Key: Images a, b and c correspond to FISH: there is positivity for MYC (a) and BCL6 (c), in this case, the signals are indicated with arrows, and there is negativity for BCL2 (b). Images d (400x) and e (400x) exhibit the negativity for Bcl2 (below 70% of marked cells) and Myc in immunohistochemistry (below 50% of marked cells). In image f (400x), there is BCL6 positivity (above 50% of marked cells). Image g (H&E, 400x): the diffuse pattern in morphology. Positivity for CD20 confirms immunophenotype B and is shown in image h (400x). Image i (400x) refers to cell proliferation rate above 90%

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Diagnostic Pathology

ISSN: 1746-1596

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