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Table 1 One-factor analysis of ADAR1

From: ADAR1 overexpression is associated with cervical cancer progression and angiogenesis

Characteristics

Case (n = 170)

Negative

Positive

P

Menopause

   

0.144

 Yes

68

16(38.23%)

52(76.47%)

 

 No

102

15(14.71%)

87(85.29%)

 

Gravidity

   

0.212

  < 3

36

4(11.11%)

32(88.89%)

 

  ≥ 3

134

27(20.15%)

107(79.85%)

 

Clinical stage

   

0.224

 I

116

24(20.69%)

92(79.31%)

 

 IIA

54

7(12.96%)

47(87.04%)

 

Tumor diameter

   

0.000**

  ≤ 4 cm

96

27(28.13%)

69(71.88%)

 

  > 4 cm

74

4(5.41%)

70(94.59%)

 

Keratinization

   

0.079

 Yes

90

12(13.33%)

78(86.67%)

 

 No

80

19(23.75%)

61(76.25%)

 

Horizontal diffusion diameter

   

0.000**

  ≤ 4 cm

102

28(27.45%)

74(72.55%)

 

  > 4 cm

68

3(4.41%)

65(95.59%)

 

Stroma invasion

   

0.612

 Superficial stroma

8

2(25.00%)

6(75.00%)

 

 Deep stroma

162

29(17.90%)

133(82.10%)

 

Vascular invasion

   

0.008*

 Negative

36

12(33.33%)

24(66.67%)

 

 Positive

134

19(14.18%)

115(85.82%)

 

Lymph node metastasis

   

0.076

 Negative

54

14(25.93%)

40(74.07%)

 

 Positive

116

17(88.73%)

99(85.34%)

 

Parametrial invasion

   

0.023*

 Negative

126

28(22.22%)

98(77.78%)

 

 Positive

44

3(6.82%)

41(93.18%)

 

Parametrial margin

   

0.855

 Negative

152

28(18.42%)

124(81.58%)

 

 Positive

18

3(16.67%)

15(83.33%)

 

Vagina margin

   

0.001**

 Negative

80

23(28.75%)

57(71.25%)

 

 Positive

90

8(88.89%)

82(91.11%)

 

Histological grade

   

0.318

 G1

30

6(20.00%)

24(80.00%)

 

 G2

52

6(11.54%)

46(88.46%)

 

 G3

88

19(21.59%)

69(78.41%)

 

HPV infection

   

0.955

 Negative

16

3(18.75%)

13(81.25%)

 

 Positive

154

28(18.18%)

126(81.82%)

 

PNI

   

0.011*

 Negative

31

31(100.00%)

0(0.00%)

 

 Positive

139

114(82.01%)

25(17.99%)

 
  1. *p < 0.05, **p < 0.01