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Table 1 Clinical and pathologic characteristics of the 13 included lesions

From: HMGA2 immunostaining is a straightforward technique which helps to distinguish pulmonary fat-forming lesions from normal adipose tissue in small biopsies: a retrospective observational study about a series of 13 lung biopsies

Case

Sex

Age (years)

Presentation

Location

HMGA2 staining

Remark

1

M

61

Smooth endobronchial lesion.

Right upper lobe

POSITIVE

 

2

M

65

ENT carcinoma. Hemoptysis. Suspicious endobronchial lesion.

Right upper lobe

POSITIVE

 

3

M

50

Hemoptysis. Small sessile endobronchial lesion.

Left lower lobe

POSITIVE

 

4

M

55

COPD and obesity. Acute pulmonary insufficiency. Non suspicious endobronchial lesion.

Right lower lobe

NEGATIVE

Superficial epithelial cells were stained.

5

M

55

COPD and obesity. Acute pulmonary insufficiency. Non suspicious endobronchial lesion.

Left upper lobe

NEGATIVE

Superficial epithelial cells were stained.

6

M

58

Small cell neuroendocrine carcinoma. Endoscopic evaluation after 6 courses of chemotherapy.

Left lower lobe

NEGATIVE

 

7

M

64

Squamous cell carcinoma of the left upper lobe. Lipomatous endobronchial lesion.

Middle lobe

POSITIVE

Superficial epithelial cells were stained.

8

F

44

Ankylosing spondylarthritis. Dyspnea. Small non suspicious endobronchial lesion.

Trachea

NEGATIVE

Superficial epithelial cells were stained.

9

F

77

Smooth pediculated endobronchial lesion. Fat density on imaging.

Left lower lobe

NEGATIVE

Superficial epithelial cells were stained.

10

M

43

Endobronchial lesion.

Left upper lobe

POSITIVE

 

11

M

77

Pediculated endobronchial lesion causing complete bronchial obstruction. Calcification on imaging. Adipose lesion macroscopically.

Right upper lobe

POSITIVE

 

12

F

9

Localized bronchiectasis. Round whitish lesion causing complete bronchial obstruction.

Left lower lobe

NEGATIVE

 

13

M

76

Incidental. Endoscopy for exposure to asbestos. Smooth endotracheal lesion with yellowish area macroscopically.

Trachea

POSITIVE

 
  1. Lesion 4 and lesion 5 were presented by the same patient
  2. M male, F female, COPD chronic obstructive lung disease