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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Epithelioid schwannoma of the skin displaying unique histopathological features: a teaching case giving rise to diagnostic difficulties on a morphological examination of a resected specimen, with a brief literature review

Fig. 3

The immunohistochemical examination of the resected specimen of cutaneous epithelioid schwannoma. a On scanning magnification (lt.) of immunohistochemistry (S-100 protein), this encapsulated vessel wall-like stroma contained no apparent schwann cells. Furthremore, immunohistochemical staining of S-100 protein could not detect any elements of apparent contiguous native perineurium of the peripheral nerve to this well-demarcated epithelioid schwannoma (Bar = 2 mm). The epithelioid tumor cells were diffusely positive for S-100 protein (rt.; Bar = 25 μm [original magnification: × 400]). b Type IV collagen was strongly reactive with reduplicated basal lamina originating from the differentiated epithelioid schwann cells (original magnification: × 400)

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Diagnostic Pathology

ISSN: 1746-1596

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