Table 1 Summary of clinical data and histomorphologic
Authors | N | Age (yr) | Sex (N) | Location (N) | Size (cm) | Symptoms | Followup/Interval (N) | Component of conventional schwannoma (N) | Mitotic activity (N) | Cytologicatypia (N) |
|---|---|---|---|---|---|---|---|---|---|---|
Orosz et al. [3] | 1 | 42 | F | Back | 1.5 | Slowly growing subcutaneous nodule | NED/15 months (1) | None | “Inconspicuous” | None |
Kindbolm et al. [4] | 5 | 23–73 | M (4), F (1) | Exteremity (3), face (1), neck of urinary bladder (1) | 1–4.5 | Painless palpable mass (4), urinary obstructive symptoms and hematuria (1) | NED/2 months to 2 years (5) | Transition to spindled areas of classic schwannoma (1) | Zero to one mitosis/10 HPF | Focally “cells with larger and more hyperchrom atic nuclei suggesting symplastic change” |
Hart et al. [2] | 58 | 14–80 | M (31), F (26) | Extremity (40), thorax/abdomen/back (10), scalp (3), neck (2), lip (1), breast (1) | 0.25–4.5 | NG | NED/NG (39), Recurrence/N G (1), Lost/NG (1) | “Epithelioid areas focally and gradually modulating with spindled areas and palisaded nuclei” (20); “other features of classic schwannomas with hyalinized and ectatic vessels” (55) | ≧3 mitoses/10 HPF (20) | “Significant nuclear atypia” (13) |
Yamada et al. | 1 | 65 | F | Extremity | 1 | Subcutaneo us nodule with tenderness | NED/9 months (1) | None | ≦1 mitosis/50 HPF | None |