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Table 1 The top 15 significantly enriched pathways for differentially expressed genes in T2D

From: A comparison of gene expression profiles in patients with coronary artery disease, type 2 diabetes, and their coexisting conditions

KEGG ID KEGG term Count FDR Genes
hsa05012 Parkinson's disease 10 1.33E-03 NDUFA5,ATP5J,NDUFV2,SNCA,NDUFA12,LRRK2,ATP5C1,UQCRB,VDAC3,UBB
hsa03010 Ribosome 8 1.41E-03 RPS3A,UBA52,RSL24D1,RPL7,RPL39,RPL21,RPS24,RPS12
hsa05200 Pathways in cancer 13 1.26E-02 PTCH1,FOS,BCL2L1,COL4A2,PTEN,BIRC3,TCF7,TCEB1,IL8,SMAD3,ITGB1,STK36,FN1
hsa05222 Small cell lung cancer 6 1.48E-02 BCL2L1,COL4A2,PTEN,BIRC3,ITGB1,FN1
hsa05016 Huntington’s disease 9 1.49E-02 NDUFA5,ATP5J,NDUFV2,NDUFA12,CREB5,ATP5C1,UQCRB,SP1,VDAC3
hsa04210 Apoptosis 6 1.50E-02 BCL2L1,BIRC3,IRAK3,DFFB,IL3RA,PRKACB
hsa05160 Hepatitis C 8 1.53E-02 STAT2,TBK1,IL8,MAVS,OAS3,OAS1,NR1H3,EIF3E
hsa04640 Hematopoietic cell lineage 6 1.56E-02 CD55,IL1R2,IL6R,TFRC,CD5,IL3RA
hsa04510 Focal adhesion 10 1.57E-02 COL4A2,PTEN,MYL12B,BIRC3,RAP1B,ARHGAP5,ITGB1,MYL12A,FN1,PPP1CC
hsa04114 Oocyte meiosis 7 1.67E-02 PPP2R5A,CDC27,SKP1,SLK,SMC3,PRKACB,PPP1CC
hsa04110 Cell cycle 7 1.76E-02 ORC3,CDC27,ORC4,SKP1,DBF4,SMAD3,SMC3
hsa03050 Proteasome 4 2.40E-02 PSMC6,POMP,PSMD12,PSMA4
hsa04120 Ubiquitin mediated proteolysis 7 2.54E-02 CDC34,CDC27,BIRC3,UBE2W,TCEB1,SKP1,CUL3
hsa04622 RIG-I-like receptor signaling pathway 5 2.56E-02 TBK1,ATG5,TANK,IL8,MAVS
hsa03013 RNA transport 7 3.28E-02 RANBP2,SRRM1,THOC7,NUP54,XPO1,POM121C,EIF3E