Fig. 4

Score 2 in endocervical adenocarcinoma. An example of Score 2b endocervical adenocarcinoma of the cervix with PD-L1 reaction involving 90% of the epithelial tumor cells (#12, Table 5). a shows the hematoxylin & eosin stain of the glandular structures with atypical epithelial cell lining and inflammatory stromal core (objective 20×). b demonstrates the membrane reaction for PD-L1 with 2+ intensity involving the epithelial tumor cells, many at cross section (objective 10×). The inset shows the circumferential membrane staining of the tumor cells for PD-L1 at a higher magnification (objective 60×)