Table 3 Univariate analyses for DFS and OS
From: Expression of signaling adaptor proteins predicts poor prognosis in pancreatic ductal adenocarcinoma
Variable | DFS | OS | ||
|---|---|---|---|---|
Median survival(months) | P | Median survival(months) | P | |
Sex | 0.700 | 0.506 | ||
Female | 10.00 | 17.00 | ||
Male | 12.00 | 17.00 | ||
Age at diagnosis | 0.725 | 0.212 | ||
≤ 60 | 12.00 | 17.00 | ||
> 60 | 10.00 | 18.00 | ||
Size (diameter), | 0.300 | 0.493 | ||
≤ 2 cm | 14.00 | 18.00 | ||
> 2 cm | 10.00 | 16.00 | ||
Tumor sites | 0.480 | 0.910 | ||
Head | 10.00 | 17.00 | ||
Body/Tail | 12.00 | 17.00 | ||
Resection margins | 0.265 | 0.013 | ||
Negative | 12.00 | 18.00 | ||
Positive | 7.00 | 13.00 | ||
Differentiation | 0.024 | 0.004 | ||
Well/moderate | 12.00 | 19.00 | ||
Poor | 7.00 | 13.00 | ||
Nodal metastasis | 0.394 | 0.076 | ||
No | 12.00 | 19.00 | ||
Yes | 8.00 | 16.00 | ||
TNM stage | 0.001 | <0.001 | ||
I/II | 12.00 | 18.00 | ||
III/IV | 5.00 | 9.00 | ||
GAB2 expression | 0.005 | 0.031 | ||
Negative | 12.00 | 20.00 | ||
Positive | 7.00 | 15.00 | ||
CRKL expression | 0.036 | 0.020 | ||
Negative | 15.00 | 20.00 | ||
Positive | 7.00 | 15.00 | ||
FRS2 expression | 0.037 | 0.003 | ||
Negative | 12.00 | 21.00 | ||
Positive | 9.00 | 15.00 | ||
GAB2/CRKL/FRS2 expression | 0.015 | 0.001 | ||
Negative | 12.00 | 18.00 | ||
Positive | 4.00 | 10.00 | ||