Table 2 22 fusion genes screened using the multi-fusion gene F-qRT-PCR assay system
From: Detection of 22 common leukemic fusion genes using a single-step multiplex qRT-PCR-based assay
Fusion genes | Also known as | Frequently associated diseases |
|---|---|---|
RUNX1-RUNX1T1 | AML1-ETO | AML M2 |
AML1-MDS1/EVI1 | Â | AML |
AML1-MTG16 | RUNX1–CBFA2T3 | AML, MDS |
BCR-ABL | Â | CML, ALL |
CBFβ-MYH11 |  | AML |
DEK-CAN | Â | AML, MDS |
E2A-HLF | Â | Pre-B ALL |
E2A-PBX1 | Â | Pre-B ALL |
MLL-AF10 | KMT2A-MLLT10 | AML M5/M4 |
MLL-AF4 | KMT2A-AFF1 | ALL, AML M4/M5 |
MLL-AF6 | KMT2A-MLLT4 | AML M4/M5, T-cell ALL |
MLL-AF9 | KMT2A-MLLT3 | AML M5a |
MLL-ELL | KMT2A-ELL | AML M4/M5 |
MLL-ENL | KMT2A-MLLT1 | AML M4/M5, B-cell ALL |
NPM-MLF | Â | AML M2/4/6, MDS |
PLZF-RARα |  | AML M3 (APL) |
PML-RARα |  | AML M3 (APL) |
STAT5b-RARα |  | AML M3 (APL) |
FIP1L1-PDGFRA | Â | CMML, CEL |
TEL-PDGFRB | Â | CMML, CEL |
SIL-TAL1 | Â | T-cell ALL |
TEL-AML1 | ETV6-RUNX1 | B-cell ALL |