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Table 1 Immunohistochemical findings obtained from the gangliocytic paraganglioma and the neuroendocrine tumor G1

From: Pancreatic gangliocytic paraganglioma harboring lymph node metastasis: a case report and literature review

 

GP in pancreatic head

NET G1 in pancreatic tail

E

G

S

Chromogranin A

+

+

+

Synaptophysin

+

+

+

S-100 protein

+

Neurofilament

+

+

ND

Pancytokeratin

+

+

ND

SSTR1

ND

SSTR2A

+

+

ND

SSTR3

ND

SSTR5

ND

Insulin

Glucagon

+

PP

Serotonin

ND

Somatostatin

+

+

Tyrosine hydroxylase

ND

Dopamine β-hydroxylase

ND

Dopa decarboxylase

ND

Phenylethanolamine N-methyltransferase

+

ND

PgR

+

+

+

  1. GP gangliocytic paraganglioma, NET neuroendocrine tumor, G1 grade 1, E epithelioid cells, G ganglion-like cells, S spindle cells, SSTR somatostatin receptor, PP pancreatic polypeptide, PgR Progesterone receptor, + positive, − negative; ND Not done