Table 2 Summary of immnohistochemical findings in previouse reports and present cases
From: Ciliated muconodular papillary tumors of the lung with KRAS/BRAF/AKT1 mutation
Author | TTF-1 | Ki67 | CK7 | CK20 | MUC5AC | MUC5B | p53 | HNF4α | p63/p40 | CDX2 | PD-L1 | ALK | BRAF V600E |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sato et al. [8] | 2/2 | 3%; 10% | 2/2 | 0/2 | 1/2 | - | - | - | - | - | - | - | - |
Chuang et al. [14] | 1/1 | <1% | 1/1 | 0/1 | - | - | 0/1 | - | 1/1 | - | - | - | - |
Chu et al. [13] | 1/1 | - | 1/1 | 0/1 | - | - | - | - | 1/1 | - | - | - | - |
Kon et al. [12] | 5/5 | <1%; 5 | 5/5 | 0/5 | 0/5 | - | 0/5 | - | 5/5 | - | - | - | - |
Lau et al. [15] | 1/1 | not increase | 1/1 | 0/1 | 1/1(weak) | - | - | - | 1/1 | - | - | - | - |
Kamata et al. [4, 11] | +a | - | - | - | +a (cliated cells) | - | - | 0/10a | +a | - | - | - | 4/4b |
Ishikawa et al. [16] | 3/5 | <5% 3; <10% 1 | 5/5 | 0/5 | - | - | 3/3 | - | - | - | - | - | - |
Taguchi et al. [10] | 0/1 | 3.7% | 1/1 | 0/1 | 1/1 | - | <1% | - | 1/1 | - | - | 1/1 | 0/1 |
Jin et al. [6] | 1/1 | - | 1/1 | - | - | - | - | - | 1/1 | - | - | 1/1 | - |
Our series | 4/4 | <5% 3; <10% 1 | 4/4 | 0/4 | 4/4 | 4/4 | 1/4 | 4/4 | 4/4d | 0/4 | <1% 4/4 | 0/4 | 1/4c |