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Table 4 BRAFV600E expression in thyroid nodular hyperplasias and follicular cell-derived carcinomas

From: cMYC expression in thyroid follicular cell-derived carcinomas: a role in thyroid tumorigenesis

BRAFV600E expression

NH (n = 25)

PTC (n = 25)

FC (n = 25)

OvFC (n = 25)

UDC (n = 21)d

Positive

0

15

0

1

11

Negative

25

10

25

24

10

P valuea (NH vs. other)

 

0.0001

1

1

0.0004

P valueb (PTC vs. other)

  

0.0001

0.0001

0.77

P valuec (UDC vs. other)

  

0.0001

0.0004

 
  1. BRAFV600E expression was compared between different groups, as shown above (a NH versus thyroid carcinomas, b PTC versus other thyroid carcinomas, c UDC versus FC and OC), using Fisher’s exact test. d One case was excluded from UDC category secondary to TMA tissue loss
  2. NH nodular hyperplasia, PTC papillary thyroid carcinoma, FC follicular carcinoma, OvFC oncocytic variant of follicular carcinoma, UDC undifferentiated carcinoma
  3. Statistically significant P values are in bold
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Diagnostic Pathology

ISSN: 1746-1596

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