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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Is hematoxylin-eosin staining in rectal mucosal and submucosal biopsies still useful for the diagnosis of Hirschsprung disease?

Fig. 1

Histological patterns in HD disease - a HD negative by HE staining: ganglion cells located in the submucosal region (black arrow) at a magnification of 40×; b HD negative by AChE assay at a magnification of 10×; c HD negative by calretinin staining: ganglion cells (black arrow) and nerve fibers (red arrow) in the lamina propria at a magnification of 10×; d HD positive by HE staining: nerve trunks in the submucosal region (black arrow) at a magnification of 10×; e HD positive by AChE assay: nerve trunks (black arrow) and fibrils (red arrow) at a magnification of 20×; f HD positive by calretinin staining at a magnification of 10×

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