Fig. 2

Cytomorphology of nucleoli in cutaneous melanoma cells. Prominent macronucleoli in melanoma cells ((a), H&E staining, ×400; insert: eosinophilic roundish macronucleolus, H&E staining, ×600). Melanoma cells of high heterogeneity in the context of cytomorphological parameters of the nucleoli – cells with micronucleoli and cells with prominent macronucleoli present ((b), H&E staining, ×400; insert: H&E staining, ×600). High representation of cancer cells with distinct nucleoli with the feature of binucleolization ((c), H&E staining, ×400; insert: H&E staining, ×600; (d) staining, ×400; insert: eosinophilic micronucleoli, H&E staining, ×600);