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Table 1 Association between clinicopathological parameters and PD-L1 expression in 373 PDAC patients

From: PD-L1 in pancreatic ductal adenocarcinoma: a retrospective analysis of 373 Chinese patients using an in vitro diagnostic assay

Clinicopathological characteristics

Total

PD-1

p value

PD-L1

p value

Positive

Negative

Positive

Negative

total

373

27

346

 

12

361

 

Age (years)

373

  

0.924

  

0.550

 Mean ± SD

 

60.12 ± 9.96

59.93 ± 9.39

 

58.42 ± 8.38

60.16 ± 9.96

 

Gender

   

0.561

  

0.067

 male

215

17

198

 

10

205

 

 female

158

10

148

 

2

156

 

Smoking

   

0.568

  

0.772

 yes

132

11

121

 

4

128

 

 no

238

16

222

 

6

232

 

Drinking

   

0.236

  

0.139

 yes

65

7

58

 

0

65

 

 no

305

20

285

 

10

295

 

History of pancreatitis

   

0.001

  

0.868

 yes

1

1

0

 

0

1

 

 no

370

26

344

 

10

360

 

Family history

   

0.528

  

0.371

 yes

5

0

5

 

0

5

 

 no

366

27

339

 

10

356

 

WBC (×109)

   

0.891

  

0.750

 >10

30

2

28

 

1

29

 

 4–10

245

21

224

 

6

239

 

 <4

19

2

17

 

1

18

 

Tumor differentiation

   

0.150

  

0.820

 moderate /poor

307

20

287

 

10

297

 

 well

59

7

52

 

1

58

 

pT

   

0.494

  

0.586

 1

2

0

2

 

0

2

 

 2

18

0

18

 

1

17

 

 3

340

26

314

 

10

330

 

 4

8

1

7

 

0

8

 

Clinical staging

   

1.000

  

1.000

 1

10

0

10

 

0

10

 

 2

329

25

304

 

11

318

 

 3

13

1

12

 

0

13

 

 4

15

1

14

 

0

15

 

Lymph node metastasis

   

0.759

  

0.058

 yes

192

13

179

 

8

184

 

 no

90

7

83

 

0

90

 

Lymphovascular invasion

   

1.000

  

1.000

 yes

28

2

26

 

0

28

 

 no

135

11

124

 

4

131

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