Clinicopathological characteristics | Total | PD-1 | p value | PD-L1 | p value | ||
---|---|---|---|---|---|---|---|
Positive | Negative | Positive | Negative | ||||
total | 373 | 27 | 346 | Â | 12 | 361 | Â |
Age (years) | 373 | Â | Â | 0.924 | Â | Â | 0.550 |
 Mean ± SD |  | 60.12 ± 9.96 | 59.93 ± 9.39 |  | 58.42 ± 8.38 | 60.16 ± 9.96 |  |
Gender | Â | Â | Â | 0.561 | Â | Â | 0.067 |
 male | 215 | 17 | 198 |  | 10 | 205 |  |
 female | 158 | 10 | 148 |  | 2 | 156 |  |
Smoking | Â | Â | Â | 0.568 | Â | Â | 0.772 |
 yes | 132 | 11 | 121 |  | 4 | 128 |  |
 no | 238 | 16 | 222 |  | 6 | 232 |  |
Drinking | Â | Â | Â | 0.236 | Â | Â | 0.139 |
 yes | 65 | 7 | 58 |  | 0 | 65 |  |
 no | 305 | 20 | 285 |  | 10 | 295 |  |
History of pancreatitis | Â | Â | Â | 0.001 | Â | Â | 0.868 |
 yes | 1 | 1 | 0 |  | 0 | 1 |  |
 no | 370 | 26 | 344 |  | 10 | 360 |  |
Family history | Â | Â | Â | 0.528 | Â | Â | 0.371 |
 yes | 5 | 0 | 5 |  | 0 | 5 |  |
 no | 366 | 27 | 339 |  | 10 | 356 |  |
WBC (×109) |  |  |  | 0.891 |  |  | 0.750 |
 >10 | 30 | 2 | 28 |  | 1 | 29 |  |
 4–10 | 245 | 21 | 224 |  | 6 | 239 |  |
 <4 | 19 | 2 | 17 |  | 1 | 18 |  |
Tumor differentiation | Â | Â | Â | 0.150 | Â | Â | 0.820 |
 moderate /poor | 307 | 20 | 287 |  | 10 | 297 |  |
 well | 59 | 7 | 52 |  | 1 | 58 |  |
pT | Â | Â | Â | 0.494 | Â | Â | 0.586 |
 1 | 2 | 0 | 2 |  | 0 | 2 |  |
 2 | 18 | 0 | 18 |  | 1 | 17 |  |
 3 | 340 | 26 | 314 |  | 10 | 330 |  |
 4 | 8 | 1 | 7 |  | 0 | 8 |  |
Clinical staging | Â | Â | Â | 1.000 | Â | Â | 1.000 |
 1 | 10 | 0 | 10 |  | 0 | 10 |  |
 2 | 329 | 25 | 304 |  | 11 | 318 |  |
 3 | 13 | 1 | 12 |  | 0 | 13 |  |
 4 | 15 | 1 | 14 |  | 0 | 15 |  |
Lymph node metastasis | Â | Â | Â | 0.759 | Â | Â | 0.058 |
 yes | 192 | 13 | 179 |  | 8 | 184 |  |
 no | 90 | 7 | 83 |  | 0 | 90 |  |
Lymphovascular invasion | Â | Â | Â | 1.000 | Â | Â | 1.000 |
 yes | 28 | 2 | 26 |  | 0 | 28 |  |
 no | 135 | 11 | 124 |  | 4 | 131 |  |