Table 3 MS assay sensitivity tested with reference standard DNA using decreasing percentages of mutated alleles
From: Molecular profiling of lung cancer specimens and liquid biopsies using MALDI-TOF mass spectrometry
| Â | Percentages of the mutated allele | |||
|---|---|---|---|---|
Reference standard | 50% | 10% | 5% | 2.5% |
EGFR G719A (c.2156 G > C) | D | D | D | D |
EGFR L861Q (c.1582 T > A) | D | D | ND | ND |
EGFR T790 M (c.2369C > T) | D | D | D | D |
KRAS Q61L (c.182 A > T) | D | D | ND | ND |
BRAF V600E (c. 1799 T > A) | D | D | ND | ND |