Table 4 MS assay sensitivity considering various percentages of mutated alleles with serially diluted DNAs from three FFPE sample cases
From: Molecular profiling of lung cancer specimens and liquid biopsies using MALDI-TOF mass spectrometry
Template DNA amount (ng) | KRAS G12C | EGFR L858R | PIK3CA H1047R | |
|---|---|---|---|---|
40 | 30% | 20% | 10% | 9% |
20 | D | D | D | D |
10 | D | D | D | ND |
5 | D | D | D | ND |