Item | n | claudin-2 (high) | claudin-2 (low) | P | n | claudin-5 (high) | claudin-5 (low) | P |
---|---|---|---|---|---|---|---|---|
Nasopharyngeal carcinoma tissue | 70 | 17 | 53 | < 0.01 | 70 | 21 | 49 | < 0.01 |
Mucosae | 70 | 32 | 38 | Â | 70 | 42 | 28 | Â |
Age (years) | Â | Â | Â | Â | Â | Â | Â | Â |
≤60 | 37 | 10 | 27 | 0.896* | 37 | 9 | 28 | 0.364* |
> 60 | 33 | 7 | 26 |  | 33 | 12 | 21 |  |
Histological grade | Â | Â | Â | Â | Â | Â | Â | Â |
Well-differentiated | 31 | 9 | 22 | 0.472* | 31 | 10 | 21 | 1.000* |
Moderately and poorly differentiated | 39 | 8 | 31 | Â | 39 | 11 | 28 | Â |
Lymph node metastasis | Â | Â | Â | Â | Â | Â | Â | Â |
– | 21 | 6 | 15 | 0.792* | 21 | 4 | 17 | < 0.05 |
– | 49 | 11 | 38 |  | 49 | 17 | 32 |  |
Ki67 | Â | Â | Â | Â | Â | Â | Â | Â |
+ | 22 | 5 | 17 | 1.000* | 22 | 6 | 16 | 1.000* |
– | 48 | 12 | 36 |  | 48 | 15 | 33 |  |
Clinical stage | Â | Â | Â | Â | Â | Â | Â | Â |
I~II | 27 | 7 | 20 | 0.364* | 27 | 5 | 22 | < 0.01 |
III~IV | 43 | 10 | 33 | Â | 43 | 16 | 27 | Â |